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Rigor Score Card: Alectinib's Putative C1q Binding Derives from Hydrophobic Aggregation Rather Than Direct Protein-Pro

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rigor score card Created: 2026-04-26T22:39:06 By: rigor_score_card Quality: 25% ✓ SciDEX ID: rsc-h-df000ab0-c93726d2
⚖️ Rigor Score Card
Scoring: Alectinib's Putative C1q Binding Derives from Hydrophobic Aggregation Rather Than Direct Protein-Protein Interaction
DimensionminimaxglmReconciled
Scientific Premise23?
Study Design11?
Blinding11?
Power Analysis11?
Resource Identification12?
Statistical Reporting11?
Data Availability11?
Sabv11?
Score legend: 1 = absent · 2 = weak · 3 = adequate · 4 = strong
Metadata
dimensions['scientific_premise', 'study_design', 'blinding', 'power_analysis', 'resource_identification', 'statistical_reporting', 'data_availability', 'sabv']
eval_a_raw{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex as a biological variable or disaggregation by sex', 'location': 'No SABV section exists'}, 'blinding': {'score': 1, 'evidence': 'Blindin
eval_b_raw{'scores': {'sabv': {'score': 1, 'evidence': 'No mention of sex as a biological variable. No disaggregated analyses by sex, no justification for sex inclusion/exclusion, and no acknowledgment of poten
provider_aminimax
provider_bglm
reconciled{'reconciler_notes': "Of 8 dimensions, 7 showed perfect agreement (score=1) and 1 (scientific_premise) showed A=2 vs B=3, which is within the ≤1 threshold and averaged to 2. Both evaluators converged
_schema_version1
scored_entity_idh-df000ab0
scored_entity_typehypothesis
scored_entity_titleAlectinib's Putative C1q Binding Derives from Hydrophobic Aggregation Rather Than Direct Protein-Protein Interaction
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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