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Alison M. Goate

wiki page Created: 2026-04-02 13:40:08 By: crosslink-migration Quality: 50% ✓ SciDEX ID: wiki-researchers-alison-goate
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entity_typeresearcher
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Linked Artifacts (43)
mentions🧪Targeted APOE4-to-APOE3 Base Editing Therapy50%
mentions🧪APOE4-Selective Lipid Nanoemulsion Therapy50%
mentions🧪APOE Isoform Expression Across Glial Subtypes50%
mentions🧪TREM2-Dependent Microglial Senescence Transition50%
mentions🧪Cell-Type Specific TREM2 Upregulation in DAM Microglia50%
related🔬What are the mechanisms underlying selective vulnerability o50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🔬What are the mechanisms underlying selective vulnerability o50%
related🔬What are the mechanisms underlying blood-brain barrier trans50%
related🔬What are the mechanisms underlying apoe4 structural biology 50%
related🔬What are the mechanisms underlying synaptic pruning by micro50%
related🔬Investigate prion-like spreading of tau pathology through co50%
related🧪APOE Isoform Conversion Therapy50%
related🧪APOE-TREM2 Interaction Modulation50%
related🧪TREM2-Mediated Selective Aggregate Clearance Pathway50%
mentions🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer45%
mentions🧪APOE4 Allosteric Rescue via Small Molecule Chaperones45%
mentions🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction45%
mentions🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides45%
mentions🧪Competitive APOE4 Domain Stabilization Peptides45%
mentions🧪TREM2 Conformational Stabilizers for Synaptic Discrimination45%
mentions🧪TREM2-mediated microglial tau clearance enhancement45%
mentions📖Alzheimer's Disease40%
mentions📖Neurodegeneration40%
mentions📖Parkinson's Disease40%
mentions📖TREM2 — Triggering Receptor Expressed on Myeloid Cells 240%
mentions📖Parkin40%
related🧪TREM2 Conformational Stabilizers for Synaptic Discrimination40%
related🧪Selective APOE4 Degradation via Proteolysis Targeting Chimer40%
related🧪APOE4 Allosteric Rescue via Small Molecule Chaperones40%
related🧪Interfacial Lipid Mimetics to Disrupt Domain Interaction40%
related🧪TREM2-mediated microglial tau clearance enhancement40%
related🧪Engineered Apolipoprotein E4-Neutralizing Shuttle Peptides40%
related🧪Competitive APOE4 Domain Stabilization Peptides40%
related🧪LRP1-Dependent Tau Uptake Disruption40%
related🧪Extracellular Vesicle Biogenesis Modulation40%
related🧪TREM2-mediated microglial tau clearance enhancement40%
related🧪Perforant Path Presynaptic Terminal Protection Strategy40%
related🧪Reelin-Mediated Cytoskeletal Stabilization Protocol40%
related🧪Tau-Independent Microtubule Stabilization via MAP6 Enhanceme40%
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