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In late life, NfL demonstrated the strongest association with incident dementia (HR 1.92 per SD higher), exceeding associations of AD-specific biomarkers.

active
experiment Created: 2026-04-27T23:22:52 By: etl-v1-backfill Quality: 50% ✓ SciDEX ID: exp-2da75ff43e71
🧫 Experiment Protocol ClinicalAlzheimer's diseasehumanextracted
NfL = neurofilament light chain; late-life biomarkers measured from 2011-2013 specimens with dementia follow-up through 2016-2019
PRIMARY OUTCOME
In late life, NfL demonstrated the strongest association with incident dementia (HR 1.92 per SD higher), exceeding associations of AD-specific biomarkers.
Source: pmid_39068543
🧫 Experiment Extras
PATHWAY
neurodegeneration
MARKET PRICE
$0.50
STATUS
extracted
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableexperiments
_schema_version1
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting 0 contradicting 0 neutral
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