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Cell type-specific analysis identified early-phase loss of somatostatin+ inhibitory neurons and later-phase loss of excitatory neurons and Pvalb+/Vip+ inhibitory neuron subtypes across AD progression.

active
experiment Created: 2026-04-27T23:23:53 By: etl-v1-backfill Quality: 50% ✓ SciDEX ID: exp-4f0a8bf4d60f
🧫 Experiment Protocol Gene ExpressionAlzheimer's diseasehumanextracted
Multiomics and spatial genomics used to profile cell populations
PRIMARY OUTCOME
Cell type-specific analysis identified early-phase loss of somatostatin+ inhibitory neurons and later-phase loss of excitatory neurons and Pvalb+/Vip+ inhibitory neuron subtypes across AD progression.
Source: pmid_39402379
🧫 Experiment Extras
PATHWAY
neuronal loss
MARKET PRICE
$0.50
STATUS
extracted
Metadataorigin_type: v1_polymorphic_backfill
origin_typev1_polymorphic_backfill
source_tableexperiments
_schema_version1
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
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Outgoing
0
0 supporting 0 contradicting 0 neutral
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