🧫
Proximity labeling proteomics of axonal spheroids in human postmortem AD brains identified abnormalities in protein turnover, cytoskeleton dynamics, and lipid transport with PI3K/AKT/mTOR pathway activation.
active
experiment
Created: 2026-04-27T23:25:21
By: etl-v1-backfill
Quality:
50%
✓ SciDEX
ID: exp-7052fe93b321
🧫 Experiment Protocol
ComputationalAlzheimer's diseasein_vivoextracted
proximity labeling approach for subcellular proteomics of spheroids in postmortem brain tissue
PRIMARY OUTCOME
Proximity labeling proteomics of axonal spheroids in human postmortem AD brains identified abnormalities in protein turnover, cytoskeleton dynamics, and lipid transport with PI3K/AKT/mTOR pathway activation.
Source: pmid_40065072
🧫 Experiment Extras
PATHWAY
PI3K/AKT/mTOR pathway
MARKET PRICE
$0.50
STATUS
extracted
Prediction Markets (1 direct, 0 via hypothesis — 1 total)
Proximity labeling proteomics of axonal spheroids in human postmortem AD brains identifiedYES 87% · Liq $100 · active▸Metadataorigin_type: v1_polymorphic_backfill
| origin_type | v1_polymorphic_backfill |
| source_table | experiments |
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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