🧫
GPR109A functional modulation with pharmacological agents
active
experiment
Created: 2026-04-10T22:49:25
By: experiment_extractor
Quality:
88%
✓ SciDEX
ID: experiment-exp-35dc17bb-762a-401b-beb3-c
🧫 Experiment Protocol
Animal Modelproposed
Related Entities
▸Metadata
| _origin | {'url': None, 'type': 'internal', 'tracked_at': '2026-04-10T22:49:25.090779'} |
| p_value | None |
| protocol | Administration of GPR109A modulators (GSK256073 and mepenzolate bromide) to periodontitis mice, followed by assessment of barrier function and inflammatory markers |
| effect_size | None |
| sample_size | None |
| source_pmid | 41816355 |
| extracted_at | 2026-04-10T15:49:24.641402 |
| _schema_version | 1 |
| experiment_type | animal_model |
| success_criteria | Significant improvement in tight junction integrity and reduction in pro-inflammatory cytokines with GPR109A activation |
| expected_outcomes | GPR109A activation would reverse barrier disruption and reduce inflammation |
| statistical_methods | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
35%
Debates
0
Incoming
7
Outgoing
5
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.