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Periodontitis-induced colonic inflammation in mice

experiment Created: 2026-04-10 22:49:24 By: experiment_extractor Quality: 90% ✓ SciDEX ID: experiment-exp-96ca29f6-fdad-46e2-92e2-2
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Related Entities
GPR109A
Metadata
experiment_typeanimal_model
protocolLigature-induced periodontitis in mice, followed by micro-CT analysis, histological evaluation, qPCR, immunostaining, ELISA, and GC-MS/MS analysis of colonic contents
expected_outcomesPeriodontitis would downregulate GPR109A expression and disrupt intestinal barrier function
success_criteriaSignificant changes in GPR109A expression, tight junction protein localization, and inflammatory markers
sample_sizeNone
statistical_methodsNone
p_valueNone
effect_sizeNone
extracted_at2026-04-10T15:49:24.641392
source_pmid41816355
_origin{'type': 'internal', 'url': None, 'tracked_at': '2026-04-10T22:49:24.644409'}
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