🧫
GPR37 deficiency in oligodendrocytes prevented neurodegeneration in multiple PD models, reducing neuroinflammation, dopamine neuron degeneration, and behavioral deficits.
active
experiment
Created:
By: experiment_extractor
Quality:
50%
✓ SciDEX
ID: experiment-exp-ba9b61f0e27a
🧫 Experiment Protocol
Animal Modelproposed
SUMMARY
GPR37 deficiency in oligodendrocytes prevented neurodegeneration in multiple PD models, reducing neuroinflammation, dopamine neuron degeneration, and behavioral deficits.
METHODOLOGY NOTES
Genetic manipulation using GPR37-deficient oligodendrocytes tested across multiple PD animal models
tissue: substantia nigraspecies: mus_musculus
Related Entities
▸Metadatasource: {'pmid': '39913287', 'type': 'paper', 'e
| source | {'pmid': '39913287', 'type': 'paper', 'extracted_by': 'llm_extraction_v1'} |
| tissue | substantia nigra |
| species | mus_musculus |
| summary | GPR37 deficiency in oligodendrocytes prevented neurodegeneration in multiple PD models, reducing neuroinflammation, dopamine neuron degeneration, and behavioral deficits. |
| sample_size | None |
| model_system | mus_musculus |
| _schema_version | 1 |
| experiment_type | animal_model |
| methodology_notes | Genetic manipulation using GPR37-deficient oligodendrocytes tested across multiple PD animal models |
| replication_status | single_study |
| extraction_metadata | {'needs_review': False, 'extraction_date': '2026-04-28T06:44:48.700651+00:00', 'extraction_notes': '', 'extraction_confidence': 0.5} |
| statistical_evidence | None |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
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Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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