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Determinants of tissue-specific vulnerability. Why are certain neurons preferentially affected?

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open question Created: 2026-04-25T20:25:45 By: backfill_open_questions Quality: 50% ✓ SciDEX ID: open_question-191c23a9-533f-4eb3-8d05-fc

Open Question open Wiki: genes-atxn2

Determinants of tissue-specific vulnerability. Why are certain neurons preferentially affected?

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1500

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Rank #849 in genes

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0.50

Potential Impact

0.50

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Extracted from wiki page genes-atxn2

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status	open
_origin	{'url': None, 'type': 'internal', 'tracked_at': '2026-04-26T03:25:45.864543'}
field_tag	genes
source_id	genes-atxn2
sub_field	atxn2
source_kind	wiki
question_hash	c58db8531e5f7f9c1d3bba1a75b929ace9250e2a2a1bc5e63fd7b80c8a6ab26e
question_text	Determinants of tissue-specific vulnerability. Why are certain neurons preferentially affected?
importance_elo	1500
_schema_version	1
evidence_summary	Extracted from wiki page genes-atxn2
tractability_score	0.5
potential_impact_score	0.5

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