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Endosomal-Lysosomal and Autophagy Pathway in Alzheimer's Disease: A Systematic Review and Meta-Analysis.

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paper Created: 2026-04-03T00:10:32 By: crosslink_script Quality: 15% 🔗 External ID: paper-35754279
📄 Paper Details
Endosomal-Lysosomal and Autophagy Pathway in Alzheimer's Disease: A Systematic Review and Meta-Analysis.
Saffire H Krance, Che-Yuan Wu, Alison C Y Chan, Stephanie Kwong, Bing Xin Song et al.
Journal of Alzheimer's disease : JAD PubMed DOI
Abstract

BACKGROUND: The endosomal-lysosomal and autophagy (ELA) pathway may be implicated in the progression of Alzheimer's disease (AD); however, findings thus far have been inconsistent. OBJECTIVE: To systematically summarize differences in endosomal-lysosomal and autophagy proteins in the cerebrospinal fluid (CSF) of people with AD and healthy controls (HC). METHODS: Studies measuring CSF concentrations of relevant proteins in the ELA pathway in AD and healthy controls were included. Standardized mea...

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