📄
Suoquan Yishen formula attenuates ectopic lipid deposition in diabetic kidney disease by inhibiting UBC9-mediated SUMO1 modification of DRP1.
active
paper
Created:
By: unknown
Quality:
50%
✓ SciDEX
ID: paper-41461331
📄 Paper Details
Suoquan Yishen formula attenuates ectopic lipid deposition in diabetic kidney disease by inhibiting UBC9-mediated SUMO1 modification of DRP1.
Wang J, Lin N, Li X, Ma T, Yuan Y et al.
Abstract
ETHNOPHARMACOLOGICAL RELEVANCE: Pathological mitochondrial hyperfission and ectopic lipid deposition in renal tubules are critical contributors to the progression of diabetic kidney disease (DKD), with SUMO1-mediated modification of DRP1 functioning as a key driving mechanism. The traditional Chinese medicine formula Suoquan Yishen Formula (SQYSF) has demonstrated clinical efficacy in ameliorating DKD; however, it remains unclear whether it improves the mitochondrial-lipid metabolism network by ...
▸Metadata
| _schema_version | 1 |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
5%
Debates
0
Incoming
1
Outgoing
1
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.