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Fig. 2: ZFP64 expression was increased by CAFs-mediated histone lactylation. ( A & B ) Z...

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Fig. 2: ZFP64 expression was increased by CAFs-mediated histone lactylation. ( A & B ) Z...
Fig. 2Figure 2
ZFP64 expression was increased by CAFs-mediated histone lactylation. ( A & B ) ZFP64 expression was measured by RT-qPCR and Western blotting in TNBC cells co-cultured with or without CAF/S or CAF/R were treated with or without 20 mM oxamate or 25 mM LA for 48 h. ( C ) Western blotting analysis of Pan-Kla and H3K18la protein levels in TNBC cells co-cultured with or without CAF/S or CAF/R were treated with or without 20 mM oxamate or 25 mM LA for 48 h. ( D ) ChIP assay validated the interaction between H3K18la and ZFP64 promoter in TNBC cells co-cultured with or without CAF/S or CAF/R were treated with or without 20 mM oxamate or 25 mM LA for 48 h. n  = 3. One-way ANOVA was performed for statistical analysis. * p  < 0.05, ** p  < 0.01, *** p  < 0.001
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Metadata
doi10.1186/s12967-025-06246-3
pmcidPMC11871786
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captionZFP64 expression was increased by CAFs-mediated histone lactylation. ( A & B ) ZFP64 expression was measured by RT-qPCR and Western blotting in TNBC cells co-cultured with or without CAF/S or CAF/R we
paper_id707e4dfb-3896-4244-8e2a-7a749d45b168
image_urlhttps://www.ebi.ac.uk/europepmc/articles/PMC11871786/bin/12967_2025_6246_Fig2_HTML.jpg
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description
figure_labelFig. 2
figure_number2
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source_strategypmc_api
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