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FIGURE 1: SkmSTX4‐iKO male mice develop inherent insulin resistance. (a) Representative im...
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Created: 2026-04-22T16:25:04
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FIGURE 1Figure 1
SkmSTX4‐iKO male mice develop inherent insulin resistance. (a) Representative immunoblot (top) and quantification (bottom) of STX4 protein abundance across skeletal muscle depots including soleus, Tibialis anterior (TA) and gastrocnemius (GAS) alongside (b) non‐skeletal muscle organs of heart and liver from control (CTRL, grey) and skmSTX4‐iKO (iKO, red) 20‐week‐old male mice normalized against total protein lysate stained with ponceau ( n = 4–7 mice/group). (c) Delta bodyweight changes of initial weight to final weight of control (CTRL, grey) and skmSTX4‐iKO (iKO, red) 20‐week‐old male mice ( n = 12–14 mice/group). (d) Intraperitoneal insulin tolerance test (IPITT) of control (CTRL, black/grey) and skmSTX4‐iKO (iKO, red) 20‐week‐old male mice with area over the curve (AOC) bar chart ( n = 9–10 mice/group). Data in bar and line graphs shown as mean ± SD. Statistical significance was determined by unpaired two‐tailed Student's t‐ test (a, b, c and d [AOC]) and multiple t ‐test mode
▸Metadata
| doi | 10.1002/jcsm.70113 |
| pmcid | PMC12602274 |
| _origin | {'url': 'https://www.ebi.ac.uk/europepmc/articles/PMC12602274/bin/JCSM-16-e70113-g007.jpg', 'type': 'external', 'tracked_at': '2026-04-22T23:25:04.943965'} |
| caption | SkmSTX4‐iKO male mice develop inherent insulin resistance. (a) Representative immunoblot (top) and quantification (bottom) of STX4 protein abundance across skeletal muscle depots including soleus, Tib |
| paper_id | 737592f9-312c-49b8-84ba-e3db425ba162 |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC12602274/bin/JCSM-16-e70113-g007.jpg |
| image_path | |
| description | |
| figure_label | FIGURE 1 |
| figure_number | 1 |
| _schema_version | 1 |
| source_strategy | pmc_api |
| entities_mentioned |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
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