🖼
Fig. 4 — Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differe
active
paper figure
Created: 2026-04-21T18:29:40
By: paper_figures_tool
Quality:
50%
🔗 External
ID: paper-fig-paper-41692246-4
Fig. 4Figure 4
A: Histogram of the most abundant proteins measured in microglia ApoE lipoproteins. Abundance was determined by excluding common contaminants, showing differential expression compared to proteins measured in ApoE −/− microglia-conditioned media, and the protein abundance being greater than the total mean + 0.5 standard deviation threshold. Error bars represent mean ± SEM. For proteomics analysis, the following groups were analyzed: ApoE2 microglia (n = 3), ApoE3 microglia (n = 3), and ApoE4 microglia (n = 4). B: PCA of the proteome of microglia ApoE lipoproteins. Circles are colored based on the ApoE isoform and represent the 95% confidence interval. Microglia samples show clear differences in the proteome of microglia-secreted ApoE lipoproteins based on the ApoE isoform. This finding is in contrast to the proteome of astrocyte ApoE lipoproteins, suggesting that the ApoE isoform plays a greater role in the proteome of microglia ApoE lipoproteins. C: Volcano plot showing differential p
▸Metadata
| pmid | paper-41692246 |
| caption | A: Histogram of the most abundant proteins measured in microglia ApoE lipoproteins. Abundance was determined by excluding common contaminants, showing differential expression compared to proteins meas |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC12996666/bin/gr4.jpg |
| paper_title | Lipidome and proteome of astrocyte and microglia ApoE lipoprotein reveal differences based on cell type and ApoE isoform. |
| figure_label | Fig. 4 |
| figure_number | 4 |
| _schema_version | 1 |
| source_strategy | pmc_api |
📊 Evidence Profile
Evidence Balance
+0%
Certainty
0%
Debates
0
Incoming
0
Outgoing
0
0 supporting
0 contradicting
0 neutral
Public annotations (0)Annotate on Hypothes.is →
No public annotations yet.