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Fig. 4 — A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa
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Created: 2026-04-21T18:29:40
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ID: paper-fig-paper-8281d7c4ac82-4
Fig. 4Figure 4
Amcp activated PI3K/AKT-regulated apoptotic proteins. a Cells were pretreated with the indicated concentrations of Z-VAD-FMK for 4 h and then cultured with various concentrations of Amcp for another 24 h before the CCK-8 cell viability assay. b Caspase-3 levels in cells were examined with or without the presence of Z-VAD-FMK, followed by 24 h of treatment with Amcp or gemcitabine (Gem). c Cells were treated with the indicated concentrations of Amcp or gemcitabine for 24 h before Western blotting assays. The protein bands were visualized by an ECL system and analyzed using Bio-Rad Laboratories Quantity One software. * P < 0.05, ** P < 0.01.
▸Metadata
| pmid | paper-8281d7c4ac82 |
| caption | Amcp activated PI3K/AKT-regulated apoptotic proteins. a Cells were pretreated with the indicated concentrations of Z-VAD-FMK for 4 h and then cultured with various concentrations of Amcp for another |
| image_url | https://www.ebi.ac.uk/europepmc/articles/PMC7470838/bin/41401_2019_354_Fig4_HTML.jpg |
| paper_title | A novel derivative of valepotriate inhibits the PI3K/AKT pathway and causes Noxa-dependent apoptosis in human pancreatic cancer cells. |
| figure_label | Fig. 4 |
| figure_number | 4 |
| _schema_version | 1 |
| source_strategy | pmc_api |
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