Lewy Body Dementia
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10
hypotheses
0
debates
0
challenges
0
pending proposals
🧠 Top Hypotheses
All 10 →
0.91
· therapeutic
0.79
· combination
0.77
· therapeutic
SASP-Mediated Cholinergic Synapse Disruption
96% yes
💬 2
0.76
· mechanistic
Stage-Specific TREM2 Biomarker-Guided Switching — Agonist in Amyloid Phase, Antagonist in Tau Phase
💬 4
0.73
· clinical
Sleep Spindle-Synaptic Plasticity Enhancement
82% yes
💬 2
0.72
· therapeutic
0.65
· combination
0.62
· therapeutic
0.62
· therapeutic
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🔍 Knowledge Gaps
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🏆 Active Challenges
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