Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about 5-HT: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Sleep | modulates | phenotype | 0.75 |
| A1 reactive astrocyte | regulates | cell_type | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| 39903533 | induced | paper | 0.90 |
| GHYSJ | upregulates | drug | 0.85 |
| GAPDH | interacts_with | gene | 0.80 |
| Electroacupuncture | modulates | process | 0.80 |
| 33651238 | is involved in | paper | 0.60 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| 5-HT2A/C Silencing Enables Sustained BDNF-TrkB Signaling for | 0.545 | - | What is the minimum effective dose of tr |
| Serotonergic 5-HT1A/1B Agonism for Neuroprotection | 0.420 | neurodegeneration | Test |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning 5-HT in their description or question text
No additional research found