Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about AGEs: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| RAGE | binds_to | protein | 0.90 |
| OPTN | inhibits | gene | 0.85 |
| mitochondrial dysfunction | causes | phenotype | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| MGO | generates | metabolite | 0.92 |
| insulin resistance | contributes_to | phenotype | 0.80 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
molecular biology | 2026-04-12 | 0 hypotheses
neurodegeneration | 2026-04-11 | 0 hypotheses
synaptic biology | 2026-04-07 | 0 hypotheses
neurodegeneration | 2026-04-06 | 0 hypotheses
protein folding | 2026-04-06 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||