concept

AL002C

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about AL002C: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

19Connections

0Hypotheses

1Analyses

19Outgoing

0Incoming

0Experiments

1Debates

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💡 Concept Info

Name	AL002C
Key Genes/Proteins	AMYLOID_PLAQUES, TREM2
Related Diseases	NEURITE_DYSTROPHY
Related Pathways	INFLAMMATORY_RESPONSE, PROLIFERATION

Pathway Diagram

graph TD
    AL002C[AL002C]
    AL002C -->|activates| Microglia_Proliferation[Microglia Proliferation]
    AL002C -->|activates| microglia_proliferation[microglia proliferation]
    AL002C -->|activates| TREM2[TREM2]
    AL002C -->|inhibits| Microglial_Inflammatory_Respon[Microglial Inflammatory Response]
    AL002C -->|treats| Alzheimer_S_Disease[Alzheimer'S Disease]
    AL002C -->|treats| Alzheimer_s_Disease[Alzheimer's Disease]
    AL002C -->|inhibits| filamentous_plaques[filamentous plaques]
    AL002C -->|inhibits| neurite_dystrophy[neurite dystrophy]

Outgoing (19)

Target	Relation	Type	Str
microglia proliferation	activates	phenotype	0.92
Microglia Proliferation	promotes	process	0.92
Microglia Proliferation	activates	process	0.92
TREM2	activates	protein	0.90
TREM2	activates	protein	0.90
Amyloid Plaques	associated_with	phenotype	0.90
Neurite Dystrophy	associated_with	phenotype	0.90
Filamentous Plaques	associated_with	phenotype	0.88
Microglial Inflammatory Response	inhibits	process	0.87
Neurite Dystrophy	associated_with	phenotype	0.85
Alzheimer'S Disease	treats	disease	0.85
Alzheimer's Disease	treats	disease	0.82
filamentous plaques	inhibits	phenotype	0.80
neurite dystrophy	inhibits	phenotype	0.80
Alzheimer's disease	therapeutic_target_for	disease	0.70
AMYLOID_PLAQUES	inhibits	protein	0.64
PROLIFERATION	activates	pathway	0.64
NEURITE_DYSTROPHY	inhibits	phenotype	0.64
INFLAMMATORY_RESPONSE	inhibits	pathway	0.56

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (1)

Scientific analyses that reference this entity

Test Preregistration Analysis

neurodegeneration | 2026-04-27 | 7 hypotheses Top: 0.710

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (1)

Multi-agent debates referencing this entity

Test question for preregistration

closed · Rounds: 4 · Score: 0.77 · 2026-04-28

Related Research

Hypotheses and analyses mentioning AL002C in their description or question text

No additional research found