Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about atp1b3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | ATP1B3 |
| Chromosome | 3q23 |
| Protein Type | Enzyme |
| Function | Critical for maintaining the endocochlear potential |
| Amino Acids | 279 aa |
| Ensembl ID | ENSG00000069899 |
| GeneCards | ATP1B3 |
| Human Protein Atlas | ATP1B3 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtNCBI GeneHPASTRING |
Knowledge base pages for this entity
flowchart TD
ATP1B3["ATP1B3"] -->|"interacts with"| ABCB1["ABCB1"]
ATP1B3["ATP1B3"] -->|"implicated in"| neurodegeneration["neurodegeneration"]
IREB2["IREB2"] -->|"interacts with"| ATP1B3["ATP1B3"]
DNAJA1["DNAJA1"] -->|"interacts with"| ATP1B3["ATP1B3"]
ATP1B1["ATP1B1"] -->|"interacts with"| ATP1B3["ATP1B3"]
style ATP1B3 fill:#4a1a6b,stroke:#333,color:#e0e0e0
style ABCB1 fill:#4a1a6b,stroke:#333,color:#e0e0e0
style neurodegeneration fill:#006494,stroke:#333,color:#e0e0e0
style IREB2 fill:#4a1a6b,stroke:#333,color:#e0e0e0
style DNAJA1 fill:#4a1a6b,stroke:#333,color:#e0e0e0
style ATP1B1 fill:#4a1a6b,stroke:#333,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| ABCB1 | interacts_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:ATP1B3 | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| IREB2 | interacts_with | gene | 0.60 |
| DNAJA1 | interacts_with | gene | 0.60 |
| ATP1B1 | interacts_with | gene | 0.60 |
| benchmark_ot_ad_answer_key:ATP1B3 | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||