gene

CAMK1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CAMK1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

CAMK1 is a serine/threonine protein kinase with critical roles in synaptic plasticity, memory formation, and neuronal survival. Dysregulation contributes to Alzheimer's, Parkinson's, and other neurodegenerative diseases.

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🧬 Gene Info

Gene Symbol	CAMK1
Full Name	Calcium/Calmodulin-Dependent Protein Kinase I
Chromosome	3p25.3
Protein Type	Kinase
Function	is a serine/threonine protein kinase that plays critical roles in neuronal signaling, synaptic plasticity, and cellular survival.
Molecular Weight	42 kDa
Amino Acids	374 aa
UniProt ID	[Q9UHV9](https://www.uniprot.org/uniprot/Q9UHV9)
Ensembl ID	ENSG00000151092
OMIM	604347
GeneCards	CAMK1
Human Protein Atlas	CAMK1
Synapsin I	Regulation of neurotransmitter release
AMPA receptor subunits	Modulation of synaptic strength
Mitochondrial proteins	Regulation of energy metabolism
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CAMK1 — Calcium/Calmodulin-Dependent Protein Kinase I

gene · 1745 words

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Pathway Diagram

graph TD
    CAMK1["CAMK1"]
    neurodegeneration["neurodegeneration"]
    CAMK1 -->|"implicated_in"| neurodegeneration
    style CAMK1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CAMK1 in their description or question text

No additional research found