gene

CDKAL1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CDKAL1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

0Experiments

0Debates

Summary

CDKAL1 encodes a tRNA modification enzyme critical for translation fidelity and linked to diabetes and neurodegeneration

View on Wiki →

No AI portrait yet

🧬 Gene Info

Gene Symbol	CDKAL1
Full Name	CDK5 Regulatory Subunit Associated Protein 1-like 1
Chromosome	5p13.3
Protein Type	Enzyme
Function	is a human gene encoding a highly conserved tRNA modification enzyme critical for cellular protein synthesis.
Primary Expression	neurons, particularly at synapses, where local protein synthesis is essential for synaptic plasticity
Molecular Weight	56.2 kDa
Amino Acids	507 aa
UniProt ID	Q9Y5J9
NCBI Gene ID	54901
Ensembl ID	ENSG00000129625
GeneCards	CDKAL1
Human Protein Atlas	CDKAL1
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: CDKAL1 — AlphaFold Q9Y5J9 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

CDKAL1 Gene

gene · 1908 words

→

CDKAL1 Protein

protein · 585 words

→

Pathway Diagram

graph TD
    CDKAL1["CDKAL1"]
    neurodegeneration["neurodegeneration"]
    CDKAL1 -->|"implicated_in"| neurodegeneration
    style CDKAL1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning CDKAL1 in their description or question text

No additional research found