protein

CFOSPROTEIN

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CFOSPROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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🔬 Protein Info

Gene Symbol	CFOSPROTEIN
Protein Type	Transcription Factor
Function	is an immediate early gene (IEG) that encodes a transcription factor.
Primary Expression	Induced in neurons by activity, stress
Molecular Weight	~62 kDa (380 amino acids)
Amino Acids	380 aa
UniProt ID	P01100
GeneCards	CFOSPROTEIN
Human Protein Atlas	CFOSPROTEIN
6-OHDA Model	c-Fos induced in dopaminergic neurons after lesion
MPTP Model	Rapid c-Fos expression in substantia nigra
Neuroprotection	c-Fos may mediate protective responses to toxins
[Amyloid-Beta](/proteins/amyloid-beta)	Aβ induces c-Fos expression
[Tau](/proteins/tau) Pathology	Neurofibrillary tangles associated with altered c-Fos
Neuronal Activity	Abnormal c-Fos responses in AD models
Associated Diseases	neurodegeneration
Interactions	ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND, APOE, APOE3
KG Connections	43 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: CFOSPROTEIN — AlphaFold P01100 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

c-Fos Protein

protein · 551 words

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Pathway Diagram

graph TD
    CFOSPROTEIN["CFOSPROTEIN"]
    neurodegeneration["neurodegeneration"]
    CFOSPROTEIN -->|"implicated_in"| neurodegeneration
    style CFOSPROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CFOSPROTEIN in their description or question text

No additional research found