| Gene Symbol | CFOSPROTEIN |
| Protein Type | Transcription Factor |
| Function | is an immediate early gene (IEG) that encodes a transcription factor. |
| Primary Expression | Induced in neurons by activity, stress |
| Molecular Weight | ~62 kDa (380 amino acids) |
| Amino Acids | 380 aa |
| UniProt ID | P01100 |
| GeneCards | CFOSPROTEIN |
| Human Protein Atlas | CFOSPROTEIN |
| 6-OHDA Model | c-Fos induced in dopaminergic neurons after lesion |
| MPTP Model | Rapid c-Fos expression in substantia nigra |
| Neuroprotection | c-Fos may mediate protective responses to toxins |
| [Amyloid-Beta](/proteins/amyloid-beta) | Aβ induces c-Fos expression |
| [Tau](/proteins/tau) Pathology | Neurofibrillary tangles associated with altered c-Fos |
| Neuronal Activity | Abnormal c-Fos responses in AD models |
| Associated Diseases | neurodegeneration |
| Interactions | ALZHEIMER, ALZHEIMER'S DISEASE, AMYLOID, AND, APOE, APOE3 |
| KG Connections | 43 knowledge graph edges |
| Databases | GeneCardsNCBI GeneHPASTRING |
No AI portrait yet
No comments yet. Be the first to comment!