Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CI-994: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | CI-994 |
| Related Diseases | Alzheimer'S Disease, Alzheimer's Disease, Cognitive Enhancement, Cognition |
| Related Pathways | Wnt/Β-Catenin Signaling, Wnt/β-catenin Signaling, Wnt/β-catenin signaling |
Knowledge base pages for this entity
graph TD
CI_994["CI-994"]
CI_994 -->|"inhibits"| Class_I_HDACs["Class I HDACs"]
CI_994 -->|"inhibits"| HDAC1["HDAC1"]
CI_994 -->|"inhibits"| HDAC2["HDAC2"]
CI_994 -->|"inhibits"| HDAC3["HDAC3"]
CI_994 -->|"inhibits"| Hdac__Class_I_["Hdac (Class I)"]
CI_994 -->|"modulates"| Wnt___Catenin_Signaling["Wnt/Beta-Catenin Signaling"]
CI_994 -->|"modulates"| Wnt___catenin_Signaling["Wnt/beta-catenin Signaling"]
CI_994 -->|"interacts"| Blood_Brain_Barrier["Blood-Brain Barrier"]| Target | Relation | Type | Str |
|---|---|---|---|
| Class I HDACs | inhibits | enzyme | 0.95 |
| Hdac (Class I) | inhibits | enzyme | 0.95 |
| Wnt/Β-Catenin Signaling | modulates | pathway | 0.95 |
| Wnt/β-catenin Signaling | modulates | pathway | 0.92 |
| Blood-Brain Barrier | interacts_with | process | 0.92 |
| Blood-Brain Barrier | associated_with | process | 0.90 |
| Alzheimer'S Disease | treats | disease | 0.90 |
| Alzheimer's Disease | treats | disease | 0.85 |
| Cognitive Enhancement | promotes | phenotype | 0.85 |
| Cognition | upregulates | phenotype | 0.85 |
| Class I HDACs | modulates | enzyme | 0.80 |
| Wnt/β-catenin signaling | modulates | pathway | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||