gene

CIDEA

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about CIDEA: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Lipid droplet-associated protein regulating cell death, metabolism, and thermogenesis

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🧬 Gene Info

Gene Symbol	CIDEA
Full Name	Cell Death-Inducing DFFA-Like Effector A
Chromosome	18p11.21
Function	is a member of the CIDE (Cell Death-Inducing DFFA-like Effector) family of proteins that play important roles in regulating cell death, lipid metabolism, and energy homeostasis.
Primary Expression	brown adipose tissue, where it promotes lipid droplet formation and regulates thermogenesis
Subcellular Localization	CIDEA is primarily localized to lipid droplets, which are dynamic organelles storing neutral lipids including triglyceri
Amino Acids	175 aa
GeneCards	CIDEA
Human Protein Atlas	CIDEA
Tissue	Expression Level
Brown adipose tissue	Highest
Liver	High
Brain	Low-Moderate
Heart	Moderate
Kidney	Low
Associated Diseases	Alzheimer's disease
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (4)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    CIDEA["CIDEA"]
    neurodegeneration["neurodegeneration"]
    CIDEA -->|"implicated_in"| neurodegeneration
    style CIDEA fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found