Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about CIRP: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Target | Relation | Type | Str |
|---|---|---|---|
| ZBP1 | interacts_with | protein | 0.95 |
| ZBP1 | prevents | protein | 0.95 |
| Cirp-Zbp1-Panoptosis Pathway | involved_in | pathway | 0.95 |
| TLR4 | binds_to | protein | 0.90 |
| ZBP1 | binds | protein | 0.90 |
| ZBP1-TRIM32 Interaction | inhibits | mechanism | 0.85 |
| Lactic Acidemia | biomarker_for | phenotype | 0.85 |
| LACTYLATION | undergoes | process | 0.80 |
| Acute Lung Injury | biomarker_for | disease | 0.75 |
| pulmonary endothelial cells | promotes death of | cell_type | 0.70 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||