gene

CMYA5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about CMYA5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Cardiomyopathy-associated 5 gene implicated in Huntington's disease and synaptic function

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🧬 Gene Info

Gene Symbol	CMYA5
Chromosome	5q32
Protein Type	Gene
Function	is a gene that has attracted significant interest in neurodegeneration research.
Primary Expression	brain tissue, particularly in regions affected by Huntington's disease pathology such as the striatum and cortex
Subcellular Localization	Cytoplasmic with association to cytoskeletal elements
GeneCards	CMYA5
Human Protein Atlas	CMYA5
Multiple coiled-coil domains	Mediate protein-protein interactions
Proline-rich regions	Potential SH3 domain binding sites
Phosphorylation sites	Multiple serine/threonine residues for regulatory modification
Subcellular localization	Cytoplasmic with association to cytoskeletal elements
Striatum	High expression in medium spiny neurons, the cell type most vulnerable in HD
Cortex	Moderate expression across cortical layers
Hippocampus	Expression in pyramidal neurons
Associated Diseases	Huntington's disease
Databases	GeneCards UniProt NCBI Gene HPA STRING

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

CMYA5 Gene

gene · 791 words

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Pathway Diagram

graph TD
    CMYA5["CMYA5"]
    neurodegeneration["neurodegeneration"]
    CMYA5 -->|"implicated_in"| neurodegeneration
    style CMYA5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning CMYA5 in their description or question text

No additional research found