gene

COX6A2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about COX6A2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

15Connections

0Hypotheses

0Analyses

8Outgoing

7Incoming

Summary

COX6A2 Gene

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🧬 Gene Info

Gene Symbol	COX6A2
Full Name	Cytochrome c Oxidase Subunit VIa Polypeptide 2
Chromosome	16p12.2
Function	COX6A2 (Cytochrome c Oxidase Subunit VIa Polypeptide 2) encodes a nuclear-encoded subunit of cytochrome c oxidase (Complex IV), the terminal enzyme of the mitochondrial electron transport chain.
UniProt ID	COX6A2
Ensembl ID	ENSG00000165496
GeneCards	COX6A2
Human Protein Atlas	COX6A2
Associated Diseases	neurodegeneration
Interactions	ASXL1, GENES, CACNA1G, AND
KG Connections	15 knowledge graph edges
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: COX6A2 — AlphaFold COX6A2 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    COX6A2["COX6A2"]
    COX6A2 -->|"activates"| ASXL1["ASXL1"]
    COX6A2 -->|"expressed in"| Corpus_Callosum["Corpus Callosum"]
    COX6A2 -->|"expressed in"| Neural_Stem_Cell["Neural Stem Cell"]
    COX6A2 -->|"expressed in"| Stem_Cell["Stem Cell"]
    COX6A2 -->|"activates"| GENES["GENES"]
    COX6A2 -->|"activates"| Genes["Genes"]
    COX6A2 -->|"implicated in"| neurodegeneration["neurodegeneration"]
    GENES -->|"activates"| COX6A2
    CACNA1G["CACNA1G"] -->|"activates"| COX6A2
    ASXL1 -->|"activates"| COX6A2
    AND["AND"] -->|"activates"| COX6A2
    RNA["RNA"] -->|"regulates"| COX6A2

Outgoing (8)

Target	Relation	Type	Str
ASXL1	activates	gene	0.60
Epigenetic	associated_with	pathway	0.60
Stem Cell	associated_with	cell_type	0.60
App	associated_with	protein	0.60
Corpus Callosum	expressed_in	brain_region	0.55
Neural Stem Cell	expressed_in	cell_type	0.55
Stem Cell	expressed_in	cell_type	0.55
GENES	activates	gene	0.50

Incoming (7)

Source	Relation	Type	Str
CACNA1G	activates	gene	0.60
ASXL1	activates	gene	0.60
GENES	activates	gene	0.60
RNA	associated_with	gene	0.60
AND	activates	gene	0.60
CACNA1G	co_discussed	protein	0.50
RNA	regulates	gene	0.50

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found