gene

DLG5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DLG5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

DLG5 is a MAGUK family scaffolding protein involved in cell polarity, synaptic organization, and implicated in Parkinson's disease and neurodevelopment

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🧬 Gene Info

Gene Symbol	DLG5
Full Name	Discs Large Homolog 5
Chromosome	10q22.3
Protein Type	Kinase
Function	encodes a member of the membrane-associated guanylate kinase (MAGUK) family of scaffolding proteins.
Primary Expression	dopaminergic neurons
Molecular Weight	220 kDa
Amino Acids	1917 aa
Exons	32
UniProt ID	Q9NZU7
NCBI Gene ID	9231
Ensembl ID	ENSG00000154655
OMIM	604455
GeneCards	DLG5
Human Protein Atlas	DLG5
Associated Diseases	Parkinson's disease, Alzheimer's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: DLG5 — AlphaFold Q9NZU7 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

DLG5 Gene (Discs Large Homolog 5)

gene · 1521 words

→

DLG5 Protein - Discs Large Homolog 5

protein · 1336 words

→

Pathway Diagram

graph TD
    DLG5["DLG5"]
    neurodegeneration["neurodegeneration"]
    DLG5 -->|"implicated_in"| neurodegeneration
    style DLG5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

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No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DLG5 in their description or question text

No additional research found