gene

DNM1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about DNM1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

0Connections

0Hypotheses

0Analyses

0Outgoing

0Incoming

1Experiments

0Debates

Summary

Page for DNM1 Gene

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🧬 Gene Info

Gene Symbol	DNM1
Full Name	Dynamin 1
Chromosome	12p11.21
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	neurons and plays a critical role in clathrin-mediated synaptic vesicle recycling, making it fundamental to maintaining synaptic
Subcellular Localization	## Molecular Function
Amino Acids	864 aa
Exons	22 exons
UniProt ID	[Q05193](https://www.uniprot.org/uniprot/Q05193)
Ensembl ID	ENSG00000106976
OMIM	602377
GeneCards	DNM1
Human Protein Atlas	DNM1
Chromosomal location	12p11.21
Genomic size	~20 kb
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    DNM1["DNM1"]
    neurodegeneration["neurodegeneration"]
    DNM1 -->|"implicated_in"| neurodegeneration
    style DNM1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (1)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
Perampanel effect on dynamin1 phosphorylation in wild-type mice	validation	Lewy body disease	0.850	0.00	wild-type mice	proposed	N/A

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning DNM1 in their description or question text

No additional research found