gene

ELMO2

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about ELMO2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

2Connections

0Hypotheses

0Analyses

1Outgoing

1Incoming

0Experiments

0Debates

Summary

Gene encoding a scaffold protein involved in phagocytosis, cell migration, and microglial function with implications for neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	ELMO2
Full Name	Engulfment Cell Motility 2
Chromosome	20q13.12
Function	is a gene located on chromosome 20q13.
Primary Expression	Brain (neurons, microglia), Spleen, Lung, Kidney, Heart
Amino Acids	720 aa
UniProt ID	Q9Y5V1
NCBI Gene ID	63916
Ensembl ID	ENSG00000124780
OMIM	606421
GeneCards	ELMO2
Human Protein Atlas	ELMO2
N-terminal domain	Proline-rich region for protein-protein interactions
PH-like domain	Pleckstrin homology domain for membrane localization
Armadillo repeats	Mediates interactions with various binding partners
Associated Diseases	Alzheimer's disease, Parkinson's disease
KG Connections	2 knowledge graph edges
Databases	GeneCards HPA STRING

🔮 Predicted Structure: ELMO2 — AlphaFold Q9Y5V1 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

ELMO2 — Engulfment Cell Motility 2

gene · 2697 words

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Pathway Diagram

graph TD
    ELMO2["ELMO2"]
    neurodegeneration["neurodegeneration"]
    ELMO2 -->|"implicated_in"| neurodegeneration
    style ELMO2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (1)

Target	Relation	Type	Str
ds-83b31ef18d49	provides_data_for	dataset	1.00

Incoming (1)

Source	Relation	Type	Str
ds-83b31ef18d49	data_in	dataset	1.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning ELMO2 in their description or question text

No additional research found