Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about ERCC6L2: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Gene profile: ERCC6L2 - DNA repair and transcription-coupled repair gene associated with neurodegeneration, bone marrow failure, and Cockayne syndrome-like disorder
| Gene Symbol | ERCC6L2 |
| Full Name | ERCC Excision Repair 6-Like 2 |
| Aliases | Gene profile: ERCC6L2 |
| Chromosome | 9q34.3 |
| Function | DNA repair, transcription-coupled repair, chromatin remodeling |
| Primary Expression | Bone marrow, brain, liver, muscle |
| Molecular Weight | 105 kDa |
| Amino Acids | 927 aa |
| Exons | 22 |
| UniProt ID | Q3L8U1 |
| NCBI Gene ID | 151246 |
| Ensembl ID | ENSG00000171824 |
| OMIM | 615472 |
| GeneCards | ERCC6L2 |
| Human Protein Atlas | ERCC6L2 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
ERCC6L2["ERCC6L2"]
neurodegeneration["neurodegeneration"]
ERCC6L2 -->|"implicated_in"| neurodegeneration
style ERCC6L2 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||