Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about FZD5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
FZD5 is a Wnt receptor critical for neural development, synaptic function, and neuroprotection in Alzheimer's disease
No AI portrait yet
| Gene Symbol | FZD5 |
| Full Name | Frizzled Class Receptor 5 |
| Chromosome | 2q33.3 |
| Protein Type | Receptor |
| Function | encodes a seven-transmembrane receptor that serves as a key Wnt ligand receptor in the central nervous system. |
| Pathways | Wnt, Wnt signaling, Wnt pathway |
| UniProt ID | Q9ULW1 |
| NCBI Gene ID | 7852 |
| Ensembl ID | ENSG00000163235 |
| OMIM | 602453 |
| GeneCards | FZD5 |
| Human Protein Atlas | FZD5 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
FZD5["FZD5"]
neurodegeneration["neurodegeneration"]
FZD5 -->|"implicated_in"| neurodegeneration
style FZD5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning FZD5 in their description or question text
No additional research found