gene

GABRG3

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about GABRG3: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

GABRG3 (GABA-A Receptor Subunit Gamma 3): gamma-3 subunit of the GABA-A receptor, crucial for inhibitory neurotransmission, synaptic localization, and implicated in Alzheimer's disease, epilepsy, autism, and neurodegeneration.

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🧬 Gene Info

Gene Symbol	GABRG3
Full Name	GABA-A Receptor Subunit Gamma 3
Chromosome	15q12
Protein Family	Cys-loop ligand-gated ion channel family
Function	inhibitory neurotransmission
Amino Acids	460 aa
UniProt ID	P18543
NCBI Gene ID	2565
Ensembl ID	ENSG00000125505
OMIM	137144
GeneCards	GABRG3
Human Protein Atlas	GABRG3
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: GABRG3 — AlphaFold P18543 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GABRG3 Gene

gene · 1506 words

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Pathway Diagram

graph TD
    GABRG3["GABRG3"]
    neurodegeneration["neurodegeneration"]
    GABRG3 -->|"implicated_in"| neurodegeneration
    style GABRG3 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GABRG3 in their description or question text

No additional research found