gene

GABRR1

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about GABRR1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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0Hypotheses

0Analyses

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0Debates

Summary

GABRR1 gene encoding the GABA-A receptor rho1 subunit, involved in inhibitory neurotransmission and implicated in epilepsy, circadian rhythms, and neurodegenerative diseases

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🧬 Gene Info

Gene Symbol	GABRR1
Full Name	GABA-A Receptor Rho1 Subunit
Chromosome	9q33.1
Function	inhibitory neurotransmission and implicated in epilepsy
Primary Expression	various brain regions including the retina, spinal cord, suprachiasmatic nucleus, and substantia nigra
UniProt ID	P28476
GeneCards	GABRR1
Human Protein Atlas	GABRR1
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards NCBI Gene HPA STRING

🔮 Predicted Structure: GABRR1 — AlphaFold P28476 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

GABRR1 — GABA-A Receptor Rho1 Subunit

gene · 1373 words

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Pathway Diagram

graph TD
    GABRR1["GABRR1"]
    style GABRR1 fill:#1a237e,stroke:#4fc3f7,stroke-width:3px,color:#fff
    Caffeine(["Caffeine"])
    neurodegeneration["neurodegeneration"]

    Caffeine -->|"modulates"| GABRR1
    GABRR1 -->|"implicated_in"| neurodegeneration

    classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
    classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
    classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
    classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
    classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
    classDef drug fill:#1a2a2a,stroke:#80cbc4,color:#e0e0e0
    class Caffeine protein
    class neurodegeneration disease

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning GABRR1 in their description or question text

No additional research found