Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about GRIN2D: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Gene Symbol | GRIN2D |
| Full Name | Glutamate Ionotropic Receptor NMDA Type Subunit 2D |
| Chromosome | 19q13.12 |
| Function | GluN2D-containing NMDA receptors have unique functional properties |
| Primary Expression | various brainstem nuclei controlling autonomic functions - Cortex: Transient high expression during development, declining in adulthood - Cerebe |
| Molecular Weight | 175 kDa |
| Amino Acids | 356 aa |
| Gene Type | Protein coding |
| UniProt ID | Q9UQF8 |
| NCBI Gene ID | 2904 |
| Ensembl ID | ENSG00000182308 |
| OMIM | 604397 |
| GeneCards | GRIN2D |
| Human Protein Atlas | GRIN2D |
| A716V | Missense |
| Associated Diseases | neurodegeneration |
| KG Connections | 5 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
flowchart TD
N0["GRIN2D"]
N1["NMDA"]
N0 -->|"co expressed with"| N1
N2["neurodegeneration"]
N0 -->|"implicated in"| N2
classDef gene fill:#1a3a2a,stroke:#4caf50,color:#e0e0e0
classDef protein fill:#1a2a3a,stroke:#4fc3f7,color:#e0e0e0
classDef disease fill:#3a1a1a,stroke:#ef5350,color:#e0e0e0
classDef pathway fill:#2a1a3a,stroke:#ce93d8,color:#e0e0e0
classDef mechanism fill:#2a2a1a,stroke:#ffd54f,color:#e0e0e0
class N1 protein| Target | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | provides_data_for | dataset | 1.00 |
| NMDA | co_expressed_with | protein | 0.50 |
| benchmark_ot_ad_answer_key:GRIN2D | data_in | dataset_row | 0.00 |
| Source | Relation | Type | Str |
|---|---|---|---|
| ds-83b31ef18d49 | data_in | dataset | 1.00 |
| benchmark_ot_ad_answer_key:GRIN2D | data_in | dataset_row | 0.00 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||