Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GANGLIOSIDES: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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| Name | GANGLIOSIDES |
Knowledge base pages for this entity
graph TD
GANGLIOSIDES["GANGLIOSIDES"]
GANGLIOSIDES -->|"expressed in"| Spinal_Cord["Spinal Cord"]
GANGLIOSIDES -.protects against.-> Neurodegeneration["Neurodegeneration"]
GANGLIOSIDES -->|"interacts"| AMYLOID_BETA["AMYLOID-BETA"]
GANGLIOSIDES -->|"involved_in"| Amyloid_Beta_Aggregation["Amyloid-Beta Aggregation"]
GANGLIOSIDES -->|"involved_in"| Nervous_Tissue_Maintenance["Nervous Tissue Maintenance"]
GANGLIOSIDES -->|"involved_in"| Nervous_Tissue_Repair["Nervous Tissue Repair"]
GANGLIOSIDES -->|"inhibits"| Inflammatory_Reaction["Inflammatory Reaction"]
GANGLIOSIDES -->|"involved_in"| Brain_Function["Brain Function"]
Gd3_Synthase["Gd3 Synthase"] -->|"regulates"| GANGLIOSIDES
B4GALNT1["B4GALNT1"] -->|"product_of"| GANGLIOSIDES
B4GANLT1["B4GANLT1"] -->|"product_of"| GANGLIOSIDES
ST8SIA1["ST8SIA1"] -->|"product_of"| GANGLIOSIDES| Target | Relation | Type | Str |
|---|---|---|---|
| Amyloid-Beta Aggregation | involved_in | process | 0.90 |
| Spinal Cord | expressed_in | cell_type | 0.90 |
| Neurodegeneration | protects_against | disease | 0.90 |
| AMYLOID-BETA | interacts_with | protein | 0.90 |
| Nervous Tissue Maintenance | involved_in | process | 0.85 |
| Nervous Tissue Repair | involved_in | process | 0.85 |
| Inflammatory Reaction | inhibits | process | 0.85 |
| Brain Function | involved_in | process | 0.85 |
| Neurodegeneration | associated_with | disease | 0.85 |
| Parkinson's Disease | associated_with | disease | 0.85 |
| Motor Neuron Function | regulates | phenotype | 0.80 |
| Sensory Function | regulates | phenotype | 0.80 |
| Energy Balance | regulates | phenotype | 0.80 |
| Lipid Rafts | component_of | mechanism | 0.80 |
| Neurons | expressed_in | cell_type | 0.80 |
| Source | Relation | Type | Str |
|---|---|---|---|
| Gd3 Synthase | regulates | enzyme | 0.90 |
| ST8SIA1 | product_of | gene | 0.85 |
| B4GALNT1 | product_of | gene | 0.85 |
| B4GANLT1 | product_of | gene | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
neurodegeneration | 2026-04-04 | 0 hypotheses
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||