Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about GluN2B: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| Antidepressant Response | involved_in | phenotype | 0.85 |
| CaMKII | activates | protein | 0.70 |
| PINK1-PARK2-mediated mitophagy | regulates | process | 0.70 |
| PINK1 | activates | gene | 0.70 |
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| GluN2B-Mediated Thalamocortical Control of Glymphatic Tau Cl | 0.869 | neuroscience | Circuit-level neural dynamics in neurode |
| GluN2B-Mediated Microglial Activation and Tau Propagation | 0.555 | neuroscience | Circuit-level neural dynamics in neurode |
| TREM2-GluN2B Circuit: Microglial Control of Thalamocortical | 0.543 | neuroscience | Circuit-level neural dynamics in neurode |
| GluN2B-Regulated Microglial Phagocytosis of Tau Aggregates v | 0.491 | neuroscience | Circuit-level neural dynamics in neurode |
| GluN2B-Mediated Perivascular Pericyte Control of Glymphatic | 0.485 | neuroscience | Circuit-level neural dynamics in neurode |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity