Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about H2S: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
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Knowledge base pages for this entity
| Target | Relation | Type | Str |
|---|---|---|---|
| AKT | modulates | protein | 0.85 |
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| H2S/butyrate imbalance drives enteric alpha-synuclein pathol | 0.380 | parkinsons | - |
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| Single nucleus RNA-seq and ATAC-seq of postmortem PD brain tissue (n=1 | gene_expression | Parkinson's disease | 0.500 | 0.00 | postmortem_human_tissue | extracted | N/A |
| Individuals with SNCA pathogenic variants reported painful dystonia, l | genetic_association | Parkinson's disease | 0.500 | 0.00 | human | extracted | N/A |
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning H2S in their description or question text
No additional research found