gene

HNRNPL

Entity Detail — Knowledge Graph Node

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This page aggregates everything SciDEX knows about HNRNPL: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Heterogeneous nuclear ribonucleoprotein L - RNA processing gene with critical roles in alternative splicing, mRNA stability, and neurodegeneration

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🧬 Gene Info

Gene Symbol	HNRNPL
Full Name	Heterogeneous Nuclear Ribonucleoprotein L
Chromosome	19q13.31.
Function	encodes an RNA-binding protein that plays critical roles in post-transcriptional gene regulation[@liu2015].
Molecular Weight	64 kDa
Amino Acids	589 aa
UniProt ID	P14866
NCBI Gene ID	3191
Ensembl ID	ENSG00000130816
OMIM	607073
GeneCards	HNRNPL
Human Protein Atlas	HNRNPL
CA-rich elements (CARE)	Primary binding sites
AU-rich elements (ARE)	Found in 3' UTRs of mRNAs
Associated Diseases	Alzheimer's disease, Parkinson's disease, ALS
Databases	GeneCards HPA STRING

🔮 Predicted Structure: HNRNPL — AlphaFold P14866 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (3)

Knowledge base pages for this entity

Canonical Page

Pathway Diagram

graph TD
    HNRNPL["HNRNPL"]
    neurodegeneration["neurodegeneration"]
    HNRNPL -->|"implicated_in"| neurodegeneration
    style HNRNPL fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning HNRNPL in their description or question text

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