Entity Detail โ Knowledge Graph Node
This page aggregates everything SciDEX knows about HTR7PROTEIN: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
Htr7 Protein is an important component in the neurobiology of neurodegenerative diseases. This page provides detailed information about its structure, function, and role in disease processes.
| Gene Symbol | htr7 |
| Full Name | 5-Hydroxytryptamine Receptor 7 |
| Chromosome | 10q21.3 |
| Protein Family | 5-HT7 family (GPCR) |
| Protein Type | G protein-coupled receptor |
| Function | is an important component in the neurobiology of neurodegenerative diseases. |
| Subcellular Localization | Plasma membrane, dendritic shafts |
| Molecular Weight | ~45-50 kDa |
| Pathways | MAPK pathway, PI3K |
| UniProt ID | P32308 |
| NCBI Gene ID | 3363 |
| Ensembl ID | ENSG00000148680 |
| Protein Name | Serotonin Receptor 7 |
| Signal Transduction | Gs protein-coupled, stimulates adenylate cyclase |
| Associated Diseases | depression |
| KG Connections | 1 knowledge graph edges |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
HTR7PROTEIN["HTR7PROTEIN"]
neurodegeneration["neurodegeneration"]
HTR7PROTEIN -->|"implicated_in"| neurodegeneration
style HTR7PROTEIN fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
|---|---|---|---|
| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
|---|---|---|---|
| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
|---|---|---|---|---|---|---|---|
| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
|---|---|---|---|---|
| No papers found | ||||