Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about KCNQ5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
KCNQ5 (Kv7.5) is a voltage-gated potassium channel that generates the M-current, regulating neuronal excitability and implicated in Alzheimer's and Parkinson's disease.
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| Gene Symbol | KCNQ5 |
| Full Name | Potassium Voltage-Gated Channel Subfamily Q Member 5 |
| Aliases | Kv7.5, Page for KCNQ5 Protein |
| Chromosome | 6q13 |
| Primary Expression | inner ear and some neurons |
| Molecular Weight | 72 kDa |
| Amino Acids | 638 aa |
| UniProt ID | Q9NRX3 |
| NCBI Gene ID | 56479 |
| Ensembl ID | ENSG00000131808 |
| GeneCards | KCNQ5 |
| Human Protein Atlas | KCNQ5 |
| Associated Diseases | Alzheimer's disease, Parkinson's disease |
| Databases | GeneCardsHPASTRING |
Knowledge base pages for this entity
graph TD
KCNQ5["KCNQ5"]
neurodegeneration["neurodegeneration"]
KCNQ5 -->|"implicated_in"| neurodegeneration
style KCNQ5 fill:#006494,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0
style neurodegeneration fill:#455a64,stroke:#333,stroke-width:1px,color:#e0e0e0| Target | Relation | Type | Str |
|---|---|---|---|
| No outgoing edges | |||
| Source | Relation | Type | Str |
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| No incoming edges | |||
Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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| No targeting hypotheses | |||
Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity
Hypotheses and analyses mentioning KCNQ5 in their description or question text
No additional research found