gene

KIF14

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF14: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Kinesin Family Member 14 - mitotic kinesin in neurodevelopment and neurodegeneration

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🧬 Gene Info

Gene Symbol	KIF14
Full Name	Kinesin Family Member 14
Chromosome	1q32.1.
Protein Family	Kinesin family, kinesin-13 subfamily
Function	is a mitotic kinesin motor protein that plays critical roles in cell division, particularly in cytokinesis and chromosome segregation.
Primary Expression	dopaminergic neurons of the substantia nigra - Altered KIF14 expression in PD brain - KIF14 deficiency may contribute to selective vulnerability of do
UniProt ID	Q9Z2R8
NCBI Gene ID	9928
Ensembl ID	ENSG00000149596
OMIM	616789
GeneCards	KIF14
Human Protein Atlas	KIF14
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KIF14 — AlphaFold Q9Z2R8 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF14 Gene

gene · 2235 words

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Pathway Diagram

graph TD
    KIF14["KIF14"]
    neurodegeneration["neurodegeneration"]
    KIF14 -->|"implicated_in"| neurodegeneration
    style KIF14 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

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Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
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Related Papers (0)

Scientific publications cited in analyses involving this entity

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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning KIF14 in their description or question text

No additional research found