gene

KIF3A

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about KIF3A: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

KIF3A (Kinesin Family Member 3A) - Subunit of KIF3 heterotrimeric kinesin motor complex. Essential for axonal transport, ciliogenesis, and synaptic vesicle trafficking. Important for Alzheimer's and Parkinson's disease mechanisms.

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🧬 Gene Info

Gene Symbol	KIF3A
Full Name	Kinesin Family Member 3A
Chromosome	5q31.2
Primary Expression	the central nervous system, with high levels in[@takemura2022][@sheng2019]:
Amino Acids	732 aa
UniProt ID	Q9Y5R6
NCBI Gene ID	11128
Ensembl ID	ENSG00000101290
OMIM	604527
GeneCards	KIF3A
Human Protein Atlas	KIF3A
Associated Diseases	Alzheimer's disease, Parkinson's disease
Databases	GeneCards HPA STRING

🔮 Predicted Structure: KIF3A — AlphaFold Q9Y5R6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

KIF3A — Kinesin Family Member 3A

gene · 2701 words

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Pathway Diagram

graph TD
    KIF3A["KIF3A"]
    neurodegeneration["neurodegeneration"]
    KIF3A -->|"implicated_in"| neurodegeneration
    style KIF3A fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

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No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning KIF3A in their description or question text

No additional research found