entity

LOR

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about LOR: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

13Connections

0Hypotheses

4Analyses

3Outgoing

10Incoming

Outgoing (3)

Target	Relation	Type	Str
S100A8	expressed_in	gene	0.60
S100A9	expressed_in	gene	0.60
benchmark_ot_ad_answer_key:LOR	data_in	dataset_row	0.00

Incoming (10)

Source	Relation	Type	Str
Tralokinumab	upregulates	drug	0.88
CCL26	expressed_in	gene	0.60
CLDN1	expressed_in	gene	0.60
IFNG	expressed_in	gene	0.60
IL22	expressed_in	gene	0.60
IL31	expressed_in	gene	0.60
CLDN1	regulates	gene	0.60
IL4R	expressed_in	gene	0.60
AQP3	regulates	gene	0.60
benchmark_ot_ad_answer_key:LOR	data_in	dataset_row	0.00

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (4)

Scientific analyses that reference this entity

How does FUS loss-of-function in TAZ regulation contribute to ALS/FTD pathogenes

neurodegeneration | 2026-04-14 | 1 hypotheses Top: 0.606

What causes IBA1 low/negative microglia in liver disease and how does this affec

neuroinflammation | 2026-04-07 | 0 hypotheses

How does P2RY12-mediated VSMC dysfunction contribute to cerebrovascular neurodeg

neurodegeneration | 2026-04-07 | 0 hypotheses

How do astrocyte-neuron metabolic interactions change during disease progression

neurodegeneration | 2026-04-04 | 1 hypotheses Top: 0.506

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found