S100A9

Understanding Entity Pages

This page aggregates everything SciDEX knows about S100A9: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

Summary

S100A9 is a gene implicated in neurodegeneration research. Key relationships include: expressed in, activates, associated with. Associated with ALI, Als, Atherosclerosis. Connected to 88 entities in the SciDEX knowledge graph.

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graph TD
    S100A9["<b>S100A9</b>"]
    ALI{"ALI"}
    S100A9 -->|"activates"| ALI
    ALDH1A1["ALDH1A1"]
    S100A9 -->|"activates"| ALDH1A1
    brain_metastasis(["brain metastasis"])
    S100A9 -->|"activates"| brain_metastasis
    osimertinib_resistance(["osimertinib resistance"])
    S100A9 -->|"activates"| osimertinib_resistance
    lung_cancer_progression(["lung cancer progression"])
    S100A9 -->|"biomarker for"| lung_cancer_progression
    INFLAMMATION["INFLAMMATION"]
    S100A9 -->|"activates"| INFLAMMATION
    Ms{"Ms"}
    S100A9 -->|"associated with"| Ms
    Sepsis{"Sepsis"}
    S100A9 -->|"activates"| Sepsis
    S100A9 -->|"expressed in"| Ms
    Cancer{"Cancer"}
    S100A9 -->|"activates"| Cancer
    Neuroinflammation{"Neuroinflammation"}
    S100A9 -->|"expressed in"| Neuroinflammation
    Inflammation{"Inflammation"}
    S100A9 -->|"expressed in"| Inflammation
    MMP9["MMP9"]
    MMP9 -->|"associated with"| S100A9
    BAX["BAX"]
    BAX -->|"activates"| S100A9
    GENES["GENES"]
    GENES -->|"activates"| S100A9
    S100A8["S100A8"]
    S100A8 -->|"associated with"| S100A9
    APOPTOSIS["APOPTOSIS"]
    APOPTOSIS -->|"activates"| S100A9
    S100A8 -->|"activates"| S100A9
    CANCER["CANCER"]
    CANCER -->|"activates"| S100A9
    OCLN["OCLN"]
    OCLN -->|"expressed in"| S100A9
    IL1RN["IL1RN"]
    IL1RN -->|"expressed in"| S100A9
    MICROGLIA["MICROGLIA"]
    MICROGLIA -->|"expressed in"| S100A9
    MIRNAS["MIRNAS"]
    MIRNAS -->|"expressed in"| S100A9
    ASTROCYTES["ASTROCYTES"]
    ASTROCYTES -->|"expressed in"| S100A9
    style S100A9 fill:#1a3a4a,stroke:#4fc3f7,stroke-width:3px,color:#e0e0e0