gene

MAST1

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MAST1: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Microtubule Associated Serine/Threonine Kinase 1 involved in neuronal signaling

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🧬 Gene Info

Gene Symbol	MAST1
Full Name	Microtubule Associated Serine/Threonine Kinase 1
Aliases	MAST, KIAA0973
Chromosome	19p13.13.
Protein Type	Serine/Threonine Kinase
Function	is a large serine/threonine kinase that plays critical roles in cytoskeletal organization, synaptic function, and cellular signaling in the central nervous system.
Primary Expression	the central nervous system:
Amino Acids	2000 aa
UniProt ID	Q9P2N6
NCBI Gene ID	23160
Ensembl ID	ENSG00000165633
GeneCards	MAST1
Human Protein Atlas	MAST1
Associated Diseases	Alzheimer's disease, Parkinson's disease, ALS
Databases	GeneCards HPA STRING

🔮 Predicted Structure: MAST1 — AlphaFold Q9P2N6 Click to expand

AI-predicted structure from AlphaFold | Powered by Mol*

Wiki Pages (1)

Knowledge base pages for this entity

Canonical Page

MAST1 Gene

gene · 1555 words

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Pathway Diagram

graph TD
    MAST1["MAST1"]
    neurodegeneration["neurodegeneration"]
    MAST1 -->|"implicated_in"| neurodegeneration
    style MAST1 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

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Incoming (0)

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Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
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Debates (0)

Multi-agent debates referencing this entity

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Related Research

Hypotheses and analyses mentioning MAST1 in their description or question text

No additional research found