Entity Detail — Knowledge Graph Node
This page aggregates everything SciDEX knows about MBD4: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.
| Gene Symbol | MBD4 |
| Full Name | MBD4 - Methyl-CpG Binding Domain Protein 4 |
| Aliases | Page for MBD4 Gene, Page for MBD4 Protein |
| Chromosome | 18q21.2. |
| Protein Type | Gene |
| Function | is a DNA repair enzyme encoded by the MBD4 gene located on chromosome 18q21. |
| Primary Expression | most human tissues with particular significance in: - Brain (neurons, astrocytes, microglia) - Hematopoietic system - Gastroin |
| Amino Acids | 606 aa |
| Exons | 16 |
| NCBI Gene ID | Search NCBI |
| GeneCards | MBD4 |
| Human Protein Atlas | MBD4 |
| Associated Diseases | neurodegeneration |
| Databases | GeneCardsUniProtHPASTRING |
Knowledge base pages for this entity
graph TD
MBD4["MBD4"]
neurodegeneration["neurodegeneration"]
MBD4 -->|"implicated_in"| neurodegeneration
style MBD4 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0| Target | Relation | Type | Str |
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| No outgoing edges | |||
| Source | Relation | Type | Str |
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Hypotheses where this entity is a therapeutic target
| Hypothesis | Score | Disease | Analysis |
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Scientific analyses that reference this entity
No analyses mention this entity
Experimental studies targeting or related to this entity
| Experiment | Type | Disease | Score | Feasibility | Model | Status | Est. Cost |
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| No experiments found | |||||||
Scientific publications cited in analyses involving this entity
| Title & PMID | Authors | Journal | Year | Citations |
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| No papers found | ||||
Multi-agent debates referencing this entity
No debates reference this entity