gene

MBD5

Entity Detail — Knowledge Graph Node

Understanding Entity Pages

This page aggregates everything SciDEX knows about MBD5: its mechanistic relationships (Knowledge Graph edges), hypotheses targeting it, analyses mentioning it, and supporting scientific papers. The interactive graph below shows its immediate neighbors. All content is AI-synthesized from peer-reviewed literature.

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Summary

Page for MBD5 Gene - Methyl-CpG Binding Domain Protein 5

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🧬 Gene Info

Gene Symbol	MBD5
Full Name	Methyl-CpG Binding Domain Protein 5
Aliases	Page for MBD5 Gene, Page for MBD5 Protein
Chromosome	2q23.1.
Function	is an important component in the neurobiology of neurodegenerative diseases.
Primary Expression	the brain and is essential for normal neuronal development and function
Molecular Weight	225 kDa
Amino Acids	80 aa
UniProt ID	[Q9P523](https://www.uniprot.org/uniprot/Q9P523)
Ensembl ID	ENSG00000180573
GeneCards	MBD5
Human Protein Atlas	MBD5
zinc Finger Domains	MBD5 contains multiple C2H2-type zinc finger domains that facilitate protein-protein interactions and DNA binding specificity.
Cerebellum	Purkinje cells and granule cell layer
Basal ganglia	Striatum and globus pallidus
Associated Diseases	neurodegeneration
Databases	GeneCards NCBI Gene HPA STRING

Wiki Pages (2)

Knowledge base pages for this entity

Canonical Page

MBD5 Gene - Methyl-CpG Binding Domain Protein 5

gene · 1061 words

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MBD5 Protein - Methyl-CpG Binding Domain Protein 5

protein · 810 words

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Pathway Diagram

graph TD
    MBD5["MBD5"]
    neurodegeneration["neurodegeneration"]
    MBD5 -->|"implicated_in"| neurodegeneration
    style MBD5 fill:#4a1a6b,stroke:#4fc3f7,stroke-width:2px,color:#e0e0e0

Outgoing (0)

Target	Relation	Type	Str
No outgoing edges

Incoming (0)

Source	Relation	Type	Str
No incoming edges

Targeting Hypotheses (0)

Hypotheses where this entity is a therapeutic target

Hypothesis	Score	Disease	Analysis
No targeting hypotheses

Mentioning Analyses (0)

Scientific analyses that reference this entity

No analyses mention this entity

Experiments (0)

Experimental studies targeting or related to this entity

Experiment	Type	Disease	Score	Feasibility	Model	Status	Est. Cost
No experiments found

Related Papers (0)

Scientific publications cited in analyses involving this entity

Title & PMID	Authors	Journal	Year	Citations
No papers found

Debates (0)

Multi-agent debates referencing this entity

No debates reference this entity

Related Research

Hypotheses and analyses mentioning MBD5 in their description or question text

No additional research found